Managers are key to employee retention and productivity. But many companies don’t promote into management the people who would do the best job as managers. The importance of first level managers to ...

The anaphase promoting complex/cyclosome (APC/C) is a 1.5-MDa ubiquitin ligase complex that initiates sister-chromatid separation and exit from mitosis by targeting cyclin B and securin for ...

The APC/C (anaphase-promoting complex; also known as the cyclosome) is an E3 ubiquitin ligase that mediates the ubiquitylation of key substrates for their degradation by the proteasome at precise ...